Learn about topiramate, an anticonvulsant used for seizures, migraine prevention, and weight loss. Includes side effects, dose, interactions, and indications. Overview: Topiramate is used to treat or prevent seizures. It is also used to prevent migraines. It may work by affecting certain signals in the brain. Common side effects include dizziness. Topamax (topiramate) is used for seizure control, migraine prevention, and sometimes weight management. One of the most frequent side effects is a burning, prickling, or numb feeling in the hands, feet, or face. Clinicians call this paresthesia. Most common side effects: Tingling in the hands and feet, changes in taste, and appetite or weight loss are common with Topamax. These are usually temporary and often manageable with minor dose. Tell your doctor if your or your child's skin feels like it is burning, crawling, itching, or if you have numbness, prickling, pins and needles , or tingling feeling after using topiramate. Topiramate causes tingling because it blocks an enzyme involved in maintaining your body’s acid-base balance, which disrupts normal nerve signaling. This “pins and needles” sensation, called paresthesia, is the single most common side effect of the drug. Most of Topamax’s side effects are not permanent, and they go away with time. For example, fatigue (low energy) and feelings of burning or numbness in your hands and feet may go away as you. Topiramate (Topamax, Eprontia) is a medication prescribed for seizures and migraines. Mild side effects include “pins and needles” sensations (paresthesia), weight loss, and drowsiness. We describe clinical and diagnostic features of a patient with peripheral neuropathy as an adverse effect of chronic topiramate (TPM) therapy. A 37-year-old woman was presented for the control of active epilepsy (2010). Learn about Topamax (topiramate) side effects, from common tingling and brain fog to serious risks such as kidney stones.